Charité - Universitätsmedizin Berlin - BIH Computational Medicine AG
The Charité - Universitätsmedizin Berlin is a joint medical faculty, which serves both Freie Universität Berlin and Humboldt Universität zu Berlin. As one of the largest university hospitals in Europe with an important history, it plays a leading role in research, teaching and clinical care. The Charité university hospital has also made a name for itself as a modern business with certifications in the medical, clinical and management fields.
POSTDOCTORAL RESEARCHER, STATISTICAL GENETICS
We are inviting applications from outstanding postdoctoral researchers as part of the newly established Computational Medicine group at the Berlin Institute of Health at Charité University Medicine (https://www.bihealth.org).
The aim of this role is to characterise the genetic architecture of diverse aspects of human metabolism using large-scale population-based and patient data and to translate these discoveries into strategies to improve health. We use cutting-edge methods to integrate large scale genomic, metabolomic, and proteomic data to identify shared genetic regulation with common, complex diseases with the aim to discover new drug targets, indications and disease mechanisms. We are ambitious, curious and enthusiastic about promoting scientific excellence and career development in the context of happy family demands.
The successful candidate will lead high profile scientific publications, represent the team in national and international collaborations and meetings, and contribute to the supervision of junior researchers.
Development of computational workflows for processing and analysis of large-scale sequencing efforts
Integration of different types of ‘omic’ data for causal inference and prioritization of drug targets and disease mechanisms
Engagement in national and international collaboration projects of the group, including partners in Cambridge and Oxford
Development of workflows to incorporate publicly available data sets to deeply characterize genetic markers of interest
Leadership of and contribution to high impact scientific publications
Training and supervision of Master and PhD students within the group in statistical genetics
If you are fluent in written and spoken English, have strong collaboration and communication skills and ability to work independently and as part of a team to tight timelines, then apply to become part of our growing team.
Essential requirements: PhD in statistical genomics, genetic epidemiology, bioinformatics or a closely related discipline, with a proven ability to write and publish academic articles. The role requires experience in analysing genome sequence data, excellent programming skills for efficient statistical genetic and computational analyses of large-scale datasets (Python, R or similar), familiarity with statistical and mathematical model-building techniques, and an aptitude for biological inference and clinical translation.
Desirable, useful skills and experience include all of the following: whole genome and/ or exome sequencing, complex and rare disease genetics, bioinformatics pipeline development, metabolomic and proteomic data and technologies, genome-wide association studies, fine-mapping, high-throughput expression data, PheWAS, Mendelian randomisation, polygenic risk scores, functional genomics, network analysis, and machine learning approaches.
Please send all application documents, e.g. cover letter, curriculum vitae,
certificates, attestations, etc. to the following address, quoting the reference number
Charité - Universitätsmedizin Berlin
BIH- AG Computational Medicine
Prof. Claudia Langenberg
Kapelle-Ufer 2, Ebene 03 firstname.lastname@example.org
DIE CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN makes its human resources decisions based on
suitability, competence and professional performance. At the same time, it strives to increase the percentage of women in management positions and takes this into consideration where candidates are equally qualified within the limits of what is legally possible. Applications from people with a migrant background are also explicitly welcome. Severely disabled applicants are given preferential consideration in the case of candidates with equal qualifications. An extended certificate of conduct must be submitted. Any travel expenses incurred cannot be reimbursed. Data protection notice: Charité points out that personal data is stored and processed as part of the application process